Atelocollagen

Enzymatic extraction, lyophilizedORGANIC

Code: PRO-2004
Source: Porcine, organic
Packaging: 10 - 100 mg
Storage: RT

Description

  • Lyophilized atelocollagen, characterized by highly pure Type I collagen content exhibits superior physical properties (strength, elasticity) and functionality
  • The proprietary enzyme-based extraction method used removes telopeptides at the non-helical N and C termini, resulting in a triple helix configuration that exhibits reduced immunogenicity.

Applications

Suitable for:

  • Three-dimensional cell cultures
  • Collagen for cell assays (invasion assay, proliferation assay etc)
  • Promed atelocollagen used as chemoattractant in cell invasion assay. Addition of atelocollagen to the substrate (A) promotes cell migration more efficiently than regular substrate (B) as quantified in graph C

References

1. LYNN, A. K., YANNAS, I. V. & BONFIELD, W. 2004. Antigenicity and immunogenicity of collagen. Journal of Biomedical Materials Research,71B,343-354.

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